Amrita Arora was born in Thane, Maharastra. Her parents divorced when she was 6 years old and she moved to Chembur with her mother & sister Malaika Arora. Her mother, Joyce Polycarp, is a Malayali Catholic and her father, Anil Arora, was a Punjabi native to Indian border town of Fazilka, who worked in the Merchant Navy.
She completed her secondary education from Swami Vivekanand School in Chembur. Her aunt, Grace Polycarp, was the principal of the school, Mumbai. Her sister is Malaika Arora.
She married Shakeel Ladak, a businessman from construction industry in 2009. The ceremonies included a Christian wedding on 4 March 2009 followed by Mehendi on 5 March and a Muslim Nikah ceremony on the 6 March 2009. They have two sons named Azaan born on 5 February 2010 and Rayaan born on 20 October 2012.